Incoming NYU freshmen and childhood neighbors Naomi and Ely have been in love with each other their whole lives, even though Ely isn't exactly into girls. The institution of a "No Kiss List" has prevented the two from rifts in the past, but their bond is tested when they both fall for the same guy. The once-inseparable pair must figure out if their friendship is strong enough to get past such an epic predicament as they struggle with the realities of growing up.

PEOPLE PLACES THINGS tells the story of Will Henry (Jemaine Clement), a newly single graphic novelist father balancing single-parenting his young twin daughters, writers block, a classroom full students, all the while exploring and navigating the rich complexities of new love and letting go of the woman who left him.